
THERAPEUTIC MANAGEMENT OF PATIENTS INFECTED WITH SARS-CoV-2 VIRUS - A REVIEW
Author(s) -
Nicoleta Mirela Blebea,
Gabriela Mitea
Publication year - 2021
Publication title -
proceedings of cbu in medicine and pharmacy ...
Language(s) - English
Resource type - Journals
eISSN - 2695-074X
pISSN - 2695-0731
DOI - 10.12955/pmp.v2.163
Subject(s) - medicine , pandemic , outbreak , covid-19 , intensive care medicine , immune system , drug , disease , antiviral drug , virus , antibiotics , immunology , infectious disease (medical specialty) , virology , pharmacology , biology , microbiology and biotechnology
Due to the rapid outbreak of the pandemic that causes SARS-CoV-2 infection and the increased rate of morbidity and mortality as a result of this new infection, the treatments pursued in therapy must have an increased potential to inhibit the replication of this virus.
OBJECTIVES: The main objective of this article was to describe the most current drug therapies and their mechanisms of action used in the treatment of COVID-19. In this article, we have collected the latest information and multilingual international scientific discoveries about the treatment of COVID-19.
RESULTS: Several compounds can be used to treat COVID-19 in order to reduce the duration of the disease and the rate of infection, to reduce the viral load, to prevent tissue damage, to stimulate the maturation of many cells, including immune cells in the human body and to reduce its severe symptoms. The most effective treatments were based on the antiviral drugs, antimalarial drugs, anti-inflammatory drugs, analgesics drugs, glycopeptide antibiotics, anticoagulants, vitamin C and vitamin D. The simplest and most direct approach to controlling SARS-CoV-2 outbreaks is the use of passive antibodies transferred from plasma to convalescent patients. Recently, studies have been completed for several vaccines that are approved against SARS-CoV-2.
CONCLUSION: Scientists around the world are collaborating and innovating to make tests, treatments and vaccines available to the public that will save lives collectively and end this pandemic.