Open AccessImmunogenetic Aspects Of Pathogenesis Of Chronic Hcv-Infection (Review)
Author(s) -
Khamid Yakubovich Karimov,
Sevara Azimova,
Bakhtiyor U. Iriskulov
Publication year - 2012
Publication title -
european medical, health and pharmaceutical journal
Language(s) - English
Resource type - Journals
eISSN - 1804-9702
pISSN - 1804-5804
DOI - 10.12955/emhpj.v4i0.360
Subject(s) - pathogenesis , immunology , viral hepatitis , virology , medicine , chronic hepatitis , biology , virus
Viral hepatitis B and C is a relevant issue because of high prevalence and degree of chronicity, late diagnosis and poor prognosis. Today, protein products of numerous genes are involved in the pathogenesis of viral pathology of the liver. In this review, the authors analyzed 42 literature sources on genetic basis of susceptibility to various infectious diseases. Study of the role of immunogenetic factors is of great practical importance to develop methods for predicting outcomes of viral hepatitis.