Open AccessA case with Crohn’s disease-associated spondyloarthritis exhibiting enhanced pro-inflammatory cytokine responses to Toll-like receptor ligands
Author(s) -
Hajime Honjo,
Tomohiro Watanabe,
Natsuki Okai,
Masashi Kono,
Ken Kamata,
Kosuke Minaga,
Yoriaki Komeda,
Shigeyoshi Tsuji,
Masatoshi Kudo
Publication year - 2021
Publication title -
asian pacific journal of allergy and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.405
H-Index - 33
ISSN - 0125-877X
DOI - 10.12932/ap-291220-1025
Subject(s) - infliximab , medicine , cytokine , immunology , inflammatory bowel disease , peripheral blood mononuclear cell , toll like receptor , tumor necrosis factor alpha , crohn's disease , disease , immune system , pathology , biology , innate immune system , biochemistry , in vitro
Despite the high incidence of spondyloarthritis (SpA) as an extra-intestinal manifestation of Crohn's disease (CD), the immunopathogenesis of CD-associated SpA remains largely unknown.