N-acetylcysteine potentiates the tumor cytotoxicity of cytokine-induced killer cells | Zendy

Pornpimon Ek-eudomsuk | Zendy; Chonvara Chalermrujinanant | Zendy; Kitipong Soontrapa | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

N-acetylcysteine potentiates the tumor cytotoxicity of cytokine-induced killer cells

Author(s) -

Pornpimon Ek-eudomsuk,

Chonvara Chalermrujinanant,

Kitipong Soontrapa

Publication year - 2022

Publication title -

asian pacific journal of allergy and immunology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.405

H-Index - 33

ISSN - 0125-877X

DOI - 10.12932/ap-280921-1245

Subject(s) - cytokine induced killer cell , cytotoxic t cell , granzyme , granzyme b , population , cytotoxicity , perforin , biology , cytokine , cancer research , cytolysis , flow cytometry , cell culture , k562 cells , immunology , cd3 , t cell , immune system , cd8 , medicine , in vitro , biochemistry , leukemia , genetics , environmental health

Cytokine-induced killer (CIK) cells are an ex vivo expanded heterogeneous population of natural killer (NK)-like T cells that can exert potent MHC-unrestricted antitumor activity. A number of pre-clinical and clinical studies have demonstrated that CIK cells can serve as a safe and potent immunotherapy of malignant tumors. N-acetylcysteine (NAC) has been demonstrated to enhance the T-cell functions by increasing their proliferation and cytokine production.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research