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Serotonin Surge: Intravenous Escitalopram as a Rare Cause of Drug-Induced Aplastic Anaemia
Author(s) -
Murtaza Hussain,
Katherine A. Boyer,
Anoosha Ponnapalli,
Dominic Awuah,
Sina Khaneki,
Smit Deliwala,
Ghassan Bachuwa
Publication year - 2022
Publication title -
european journal of case reports in internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.125
H-Index - 1
ISSN - 2284-2594
DOI - 10.12890/2022_003228
Subject(s) - escitalopram , medicine , pancytopenia , cytopenia , aplastic anemia , pediatrics , complete blood count , blood count , drug , surgery , pharmacology , bone marrow , hippocampus , antidepressant
Escitalopram is a commonly prescribed medication that has infrequently been implicated in drug-induced thrombocytopenia (DITP) but has never been associated with aplastic anaemia in the literature. We present an extremely rare case of hypoproliferative pancytopenia due to self-administered intravenous (IV) injection of escitalopram. The crux of this case is the unusual trilineage cytopenia. Our patient was managed with steroids and supportive care with subsequent clinical and blood count recovery. This case sheds light on this uncommon but important association.

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