Open AccessAlkaline Diuresis as Treatment for 2,4-D Dimethylamine Herbicide Intoxication
Author(s) -
Apolonia Berenika Badu,
Ade Ajeng Cempakadewi,
Brigitta Marcia Budihardja,
Anselmus Ake
Publication year - 2022
Publication title -
european journal of case reports in internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.125
H-Index - 1
ISSN - 2284-2594
DOI - 10.12890/2021_003126
Subject(s) - diuresis , medicine , dimethylamine , resuscitation , intensive care medicine , anesthesia , kidney , chemistry , biochemistry
Acute intoxication with 2,4-D dimethylamine is rare, often fatal and can cause signs and symptoms in different organ systems. This case report describes the effectiveness of alkaline diuresis as a life-saving treatment for chlorophenoxy intoxication, especially in healthcare facilities without access to haemodialysis. A patient had attempted suicide by ingesting 2,4-D dimethylamine, with toxic effects on the central and peripheral nervous systems, and the gastrointestinal and respiratory systems. However, she significantly improved after alkaline diuresis, accompanied by resuscitation, decontamination of the gastrointestinal system, and supportive therapies.