Open AccessHaemophagocytic Lymphohistiocytosis as a Complication of Israeli Spotted Fever
Author(s) -
Maria Margarida de Andrade,
Ana Gorgulho,
Rita Tinoco Magalhães,
Rita Valadas,
Luís Pereira,
Sara López Freire,
Diogo Cruz
Publication year - 2022
Publication title -
european journal of case reports in internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.125
H-Index - 1
ISSN - 2284-2594
DOI - 10.12890/2021_003073
Subject(s) - rickettsia conorii , boutonneuse fever , medicine , spotted fever , hemophagocytic lymphohistiocytosis , complication , immunology , virology , pediatrics , rickettsia , pathology , virus , surgery , disease
Rickettsia spp. human infection is endemic in Portugal in the form of Mediterranean spotted fever caused by R. conorii subsp. conorii and Israeli spotted fever (ISF) caused by R. conorii subsp. israelensis. We describe a rare case of haemophagocytic lymphohistiocytosis (HLH) due to ISF, with atypical manifestations. We highlight the need for clinical suspicion for this diagnosis and the importance of timely intervention and support.