Open AccessThe Development of Ecchymosis after Administration of Convalescent Serum in a Patient with COVID-19 Associated with Thrombocytosis
Author(s) -
Rajashree Khot,
Sunita Kumbhalkar,
Richa Juneja,
Prashant Joshi
Publication year - 2021
Publication title -
european journal of case reports in internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.125
H-Index - 1
ISSN - 2284-2594
DOI - 10.12890/2021_002782
Subject(s) - thrombocytosis , medicine , ecchymosis , covid-19 , platelet , pathophysiology , disease , lymphocyte , convalescent plasma , aspirin , abnormality , immunology , gastroenterology , pathology , infectious disease (medical specialty) , psychiatry
COVID-19 can have an unpredictable and severe course, leading to many hypotheses regarding its pathophysiology and clinical manifestations. Haematological manifestations are a significant predictor of disease severity. The most common observation is lymphopenia with an increased neutrophil:lymphocyte ratio. Platelets have been implicated in thrombogenic events, but the most frequently reported abnormality is mild thrombocytopenia. Here we present an interesting case of a patient with moderate COVID-19 who presented with cutaneous ecchymoses and thrombocytosis, and discuss this paradox.