Open AccessProstate Cancer and Reactive Haemophagocytic Lymphohistiocytosis
Author(s) -
Laure Dumont,
Adriano Salaroli,
Lissandra Dal Lago,
Thierry Gil,
Thierry Pepersack
Publication year - 2021
Publication title -
european journal of case reports in internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.125
H-Index - 1
ISSN - 2284-2594
DOI - 10.12890/2021_002425
Subject(s) - medicine , hemophagocytic lymphohistiocytosis , prostate cancer , cancer , oncology , pediatrics , disease
We report the case of a 76-year-old man presenting with reactive haemophagocytic lymphohistiocytosis (rHLH) in the setting of disseminated prostate cancer. This often fatal syndrome must be diagnosed early in order to maximize survival. Treatment should be initiated whenever the clinical diagnosis is suspected, even if the HLH-2004 criteria are not met. The HScore is a useful diagnostic tool for rHLH. In case of neurological symptoms, an extensive assessment must be performed. The goal of this case report is to raise awareness of this rare syndrome among oncologists.