Open AccessDiabetic Ketoacidosis, Hypertriglyceridemia and Abdominal Pain due to Acute Pancreatitis Complicated by Non-immune Haemolytic Anaemia
Author(s) -
Monica L. Joustra,
Janneke J Raidt,
Florens Droog,
Thiemo F. Veneman
Publication year - 2020
Publication title -
european journal of case reports in internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.125
H-Index - 1
ISSN - 2284-2594
DOI - 10.12890/2020_002085
Subject(s) - medicine , acute pancreatitis , hypertriglyceridemia , diabetic ketoacidosis , abdominal pain , pancreatitis , ketoacidosis , gastroenterology , diabetes mellitus , immune system , hyperlipidemia , insulin , immunology , endocrinology , triglyceride , cholesterol , type 1 diabetes
The triad of diabetic ketoacidosis, acute pancreatitis and hypertriglyceridemia is a rare phenomenon, with mortality rates of up to 80%. A unique characteristic of the described case is the co-occurrence of non-immune haemolytic anaemia (NIHA) with the complex triad. It is suggested that this presentation is secondary to hyperlipidemia which leads to increased fragility of erythrocytes due to destabilization of red cell membranes. Supportive treatment with intravenous insulin and blood transfusions is the cornerstone of treatment.