Open AccessTracheobronchopathia Osteochondroplastica: Two Different Facets of a Rare Entity
Author(s) -
Margarida Barata,
Ricardo Gomes,
Catarina Moreira,
Jorge Soares
Publication year - 2020
Publication title -
european journal of case reports in internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.125
H-Index - 1
ISSN - 2284-2594
DOI - 10.12890/2020_001925
Subject(s) - medicine , submucosa , bronchoscopy , tracheobronchomalacia , lumen (anatomy) , stenosis , airway , airway obstruction , rare disease , chronic cough , radiology , disease , surgery , pathology , asthma
Tracheobronchopathia osteochondroplastica (TBPO) is an uncommon benign disease, characterized by osseous or metaplastic cartilaginous nodules in the submucosa of the tracheobronchial tree. TBPO is easy to misdiagnose due to its non-specific clinical manifestation. We describe two cases of TBPO. The first patient was a 57-year-old woman with nocturnal dry cough and wheezing, in whom bronchoscopy revealed small diffuse mucosal irregularities involving the airway until the segmental bronchi. The other patient was a 69-year-old man with progressive worsening dyspnoea and productive cough presenting with severe stenosis of the trachea. Histological examination of both cases was consistent with TBPO. These cases highlight distinct forms of presentation of this rare entity.