Open AccessBlue Woman Syndrome and Thyrotoxicosis in a Patient on Amiodarone
Author(s) -
Radovan Hojs,
Tadej Pedreski,
Nejc Piko,
Matevž Privšek,
Tadej Zorman,
Sebastjan Bevc
Publication year - 2020
Publication title -
european journal of case reports in internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.125
H-Index - 1
ISSN - 2284-2594
DOI - 10.12890/2020_001526
Subject(s) - amiodarone , medicine , discontinuation , adverse effect , thyroid function , thyroid , toxicity , thyroid function tests , cardiology , refractory (planetary science) , gastroenterology , anesthesia , atrial fibrillation , astrobiology , physics
Amiodarone is an antiarrhythmic drug, in use from the 1960s, which acts on potassium transport in myocytes, causing a lengthening of the action potential and refractory period. Even though it is broadly prescribed, its use is limited by a relatively high occurrence of adverse reactions such as lung, thyroid or hepatic disease, skin changes and so on. The authors report a case of a female patient who was admitted due to chest pain. Due to the bluish skin pigmentation, other causes of amiodarone toxicity were investigated, and hyperthyroidism was detected. After amiodarone discontinuation and specific therapy, thyroid function returned to normal.