Open AccessMortality among benzene-exposed workers in China.
Author(s) -
Richard B. Hayes,
Yin Song,
Mustafa Dosemeci,
Gui Lan Li,
Sholom Wacholder,
Wong Ho Chow,
Nathaniel Rothman,
Yao Zu Wang,
Tan Rong Dai,
Xin Jie Chao,
Zhong Lian Jiang,
Pei Zheng Ye,
Hong Tie Zhao,
Qing Rui Kou,
Wan You Zhang,
Juan Meng,
Jie Sheng Zho,
Xia Lin,
Cheng Ding,
Chin Yang Li,
Zhi Nan Zhang,
De Gao Li,
Lois B. Travis,
William J. Blot,
Martha S. Linet
Publication year - 1996
Publication title -
environmental health perspectives
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.961041349
Subject(s) - medicine , cohort , lung cancer , cohort study , benzene , environmental health , toxicology , cancer , chemistry , biology , organic chemistry
A large cohort of 74,828 benzene-exposed and 35,805 nonexposed workers employed between 1972 and 1987 in 12 cities in China was followed to determine mortality from all causes. Benzene-exposed study subjects were employed in a variety of occupations including coating applications, and rubber, chemical, and shoe production. Mortality was slightly increased among workers with greater cumulative exposure to benzene (ptrend < 0.05), but this excess was largely due to cancer deaths (ptrend < 0.01). Deaths due to lymphatic and hematopoietic malignancies (ptrend = 0.01) and lung cancer (ptrend = 0.01) increased with increasing cumulative exposure to benzene. Investigations continue to relate benzene exposure to specific lymphatic and hematopoietic malignancies and other causes of death.