Open AccessPredicting biological effect as a function of the chemical structure and the primary physical and chemical properties of organic compounds.
Author(s) -
N G Andreyeshcheva
Publication year - 1976
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.761327
Subject(s) - primary (astronomy) , chemical structure , basis (linear algebra) , biological system , chemistry , series (stratigraphy) , computational chemistry , organic chemistry , mathematics , biology , physics , geometry , astronomy , paleontology
The dependence of biological parameters on chemical structure was studied for a series of compounds with similar chemical structures. Computational formulas were developed on the basis of correlation and regression analysis. These formulas make it possible to predict the biological effect thresholds for a great number of organic compounds on the basis of their primary physical and chemical properties.