Open AccessIncreased Lead Biomarker Levels Are Associated with Changes in Hormonal Response to Stress in Occupationally Exposed Male Participants
Author(s) -
Marie Fortin,
Deborah A. CorySlechta,
Pamela OhmanStrickland,
Chizoba Nwankwo,
T. Steven Yanger,
Andrew C. Todd,
Jan A. Moynihan,
James Walton,
Andrew Brooks,
Nancy Fiedler
Publication year - 2012
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.1103873
Subject(s) - trier social stress test , adrenocorticotropic hormone , biomarker , stressor , medicine , endocrinology , hormone , corticosterone , physiology , hydrocortisone , lead exposure , fight or flight response , biology , cats , clinical psychology , biochemistry , gene
Lead (Pb) exposure has been associated with a host of pathological conditions in humans. In rodents Pb exposure has been shown to alter the hypothalamic-pituitary-adrenal (HPA) axis function.