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Survival of composite chondrocutaneous grafts by vessel implantation: A study in the rabbit ear model
Author(s) -
Arden Richard L.,
Smith Duane M.,
Salley Steve O.,
Sakr Wael A.,
Doerr Timothy D.
Publication year - 1995
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1288/00005537-199512000-00012
Subject(s) - revascularization , medicine , angiogenesis , surgery , anatomy , cardiology , myocardial infarction
Composite chondrocutaneous graft reconstruction or reattachment has limited applicability, is traditionally restricted to small segmental losses, and is dependent on the status of the recipient bed and graft periphery for successful revascularization. Surgical enhancement of composite graft survival was experimentally investigated in the rabbit ear model through transposition and appositional placement of an adjacent vascular pedicle. Fluorescein‐derived surface‐survival determinations, microangiographic vessel‐counting methods, and histologic analysis were used to study the effects of vascular augmentation, pedicle design variations, and angiogenic substance in sixty 8‐cm 2 , full‐thickness auricular grafts. A statistically significant survival advantage was demonstrated for the implanted grafts, without derived benefit from angiogenic substance, secondary to perivascular angiogenesis from the implanted pedicle.