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Tracheal anastomosis with the diode laser and fibrin tissue adhesive: An in vitro and in vivo investigation
Author(s) -
Gleich Lyon L.,
Wang Zhi,
Pankratov Michail M.,
Thomas Aretz H.,
Shapshay Stanley M.
Publication year - 1995
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1288/00005537-199505000-00009
Subject(s) - anastomosis , fibrin , in vivo , medicine , surgery , stenosis , wound healing , fibrosis , laser beam welding , indocyanine green , materials science , biomedical engineering , welding , pathology , radiology , biology , composite material , microbiology and biotechnology , immunology
Abstract Absorbable sutures have been advocated for tracheal anastomosis to reduce fibrosis and foreign body reaction leading to recurrent stenosis. Fibrin tissue adhesive (FTA) and diode laser welding with indocyanine green‐dyed fibrinogen were evaluated in tracheal anastomosis to reduce the number of sutures and to improve healing. In vitro studies demonstrated strong anastomoses with a combination of laser welding and FTA with minimal tissue damage. In a controlled in vivo study, circumferential resections of canine tracheas were repaired with laser welding and FTA augmented with a few stay sutures. These anastomoses had less fibrosis and tissue damage than anastomoses in control animals repaired with sutures alone. This study supports investigation of laser welding and FTA in human beings for tracheal anastomosis and other procedures in which suturing may be difficult.