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Endoscopic diode laser welding of mucosal grafts on the larynx: A new technique
Author(s) -
Wang Zhi,
Pankratov Michail M.,
Rebeiz Elie E.,
Perrault Donald F.,
Shapshay Stanley M.
Publication year - 1995
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1288/00005537-199501000-00012
Subject(s) - medicine , surgery , larynx , transplantation , stenosis , indocyanine green , cadaver , endoscopy , ex vivo , in vivo , radiology , biology , microbiology and biotechnology
Abstract Epithelial coverage of a laryngotracheal wound is an important factor in preventing stenosis, and endoscopic transplantation of a free mucosal graft without stents or sutures would be a significant therapeutic advance. In vitro and in vivo canine studies were performed to explore the feasibility of transplantation with a low‐power diode laser (400 mW) enhanced by indocyanine green dye‐doped albumin. The tensile strength of graft adherence in 10 cadaver larynges was strong (35.25 ± 10.39 g). Survival studies in live canine models with a specially designed endoscopic instrument set showed excellent healing at 6, 14, and 28 days. Healing was documented with photography and by histologic examination. Successful endoscopic transplantation of a free mucosal graft should improve results of treatment for laryngotracheal stenosis and laryngeal reconstructive surgery.