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Nasal mucosal congestion after treatment with bromocriptine
Author(s) -
Bende Mats,
Bergman Boinge,
Sjögren Christer
Publication year - 1993
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1288/00005537-199310000-00011
Subject(s) - bromocriptine , prolactin , medicine , vasoactive intestinal peptide , endocrinology , nasal administration , thyroid stimulating hormone , hormone , nasal congestion , lactation , pregnancy , pharmacology , nose , neuropeptide , receptor , biology , surgery , genetics
Nine women were given bromocriptine a few days after delivery in order to inhibit lactation. Nasal airway resistance to airflow (NAR) was recorded and blood samples were taken before treatment with bromocriptine, 2 to 3 hours after the first dose of this drug, and after 3 to 5 days on this treatment. All the women had increased nasal congestion after bromocriptine and NAR rose significantly. The prolactin, estradiol, and progesterone hormone levels decreased significantly, but no significant difference was found in the levels of thyroid‐stimulating hormone (TSH) and vasoactive intestinal polypeptide (VIP). The bromocriptine effect may be caused by different mechanisms.