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A comparison of risk factors in juvenile‐onset and adult‐onset recurrent respiratory papillomatosis
Author(s) -
Kashima Haskins K.,
Shah Farida,
Lyles Alan,
Glackin Robert,
Muhammad Nadayah,
Turner Laurie,
Van Zandt Shirley,
Whitt Sheila,
Shah Keerti
Publication year - 1992
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1288/00005537-199201000-00002
Subject(s) - recurrent respiratory papillomatosis , medicine , juvenile , young adult , age of onset , firstborn , pediatrics , human papillomavirus , biology , disease , birth order , population , genetics , environmental health
Abstract The clinical triad of a firstborn delivered vaginally to a young (teenage) mother has been previously noted among juvenile onset recurrent respiratory papillomatosis (JO‐RRP) patients. This study was based on a questionnaire survey of JO‐RRP patients, adult onset recurrent respiratory papillomatosis (AO‐RRP) patients, and juvenile and adult controls. The survey results revealed that the complete or partial triad was observed in 72% of JO‐RRP patients, 36% of AO‐RRP patients, 29% of juvenile controls, and 38% of adult controls. As compared with juvenile controls, JO‐RRP patients were more often firstborn ( P <.05), delivered vaginally ( P <.05), and born to a teenage mother ( P <.01). Among adult participants, AO‐RRP patients reported more lifetime sex partners ( P <.01) and a higher frequency of oral sex ( P <.05) than reported by adult controls. AO‐RRP and JO‐RRP appear to have distinguishable epidemiologic features indicating that the mode of human papillomavirus (HPV) transmission is different in these two disorders.