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Nonsurgical correction of auricular deformities
Author(s) -
Millay Donna J.,
Larrabee Wayne F.,
Dion E. Richard
Publication year - 1990
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1288/00005537-199008000-00020
Subject(s) - hyaluronic acid , proteoglycan , cartilage , extracellular matrix , chondroitin sulfate , chemistry , glycosaminoglycan , chondroitin , microbiology and biotechnology , biochemistry , anatomy , medicine , biology
There appears to be a sound physiologic basis reported in the literature for the success of nonsurgical reshaping of the ear shortly after birth. Cartilage is composed of a cellular component, the chondrocytes, and an extracellular matrix, consisting of collagen and proteoglycan aggregate. Proteoglycan is a macro‐molecule with a core of protein surrounded by many glycosaminoglycans (principally chondroitin sulfate and keratin sulfate) and a hyaluronic acid molecule. The proteoglycan molecule appears to be responsible for cartilage elasticity. 6 One of the substances that has been shown to increase cartilage pliability is estrogen, which directly increases hyaluronic acid levels. 7–8 At birth, there are very high circulating.