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Fibrosarcoma of the head and neck
Author(s) -
Frankenthaler Robert,
Goepfert Helmuth,
Ayala Alberto G.,
Hartwick R. Warren
Publication year - 1990
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1288/00005537-199008000-00001
Subject(s) - dermatofibrosarcoma protuberans , head and neck , fibrosarcoma , soft tissue , medicine , sarcoma , soft tissue sarcoma , pathology , surgery
A review of 118 archival cases originally diagnosed as fibrosarcoma of the head and neck is presented. Sites of involvement were the sinonasal region, upper aerodigestive tract, skin, and soft tissues. Review of the pathologic specimens applying strict histopathologic criteria including im‐munohistochemical techniques reclassified many of the tumors as malignant fibrous histiocytoma, monophasic sy‐novial sarcoma‐like neoplasm, or dermatofibrosarcoma protuberans. Improved clinical outcome correlated significantly with lesser tumor size, lower histologic grade, and negative surgical margins. Location in the skin or soft tissue tended to convey improved survival, although not to a level of statistical significance.