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Early alterations of cochlear function in experimental perilymph fistulas
Author(s) -
Böhmer Andreas
Publication year - 1990
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1288/00005537-199004000-00011
Subject(s) - round window , perilymph , inner ear , conductive hearing loss , compound muscle action potential , audiology , perforation , sudden hearing loss , hearing loss , middle ear , stimulation , cochlea , medicine , electrophysiology , anatomy , materials science , punching , metallurgy
Alterations of cochlear function secondary to perforation of the round window membrane in guinea pigs were expected to reveal sensitive and/or specific audiometric parameters in perilymph fistulas. A perforation of the round window membrane either did not affect acoustic compound action potential thresholds, or induced a delayed, possibly conductive, inner ear hearing loss. Also, evoked supra‐threshold responses deteriorated progressively and independently of the increase of compound action potential thresholds. A sudden (conductive) hearing loss and a poor response to suprathreshold stimulation might indicate inner ear damage secondary to a perilymphatic fistula.