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Adhesives in larynx repair
Author(s) -
Lyons Michael B.,
Lyons George D.,
Webster Douglas,
Wheeler Valerie R.
Publication year - 1989
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1288/00005537-198904000-00003
Subject(s) - cyanoacrylate , glue , adhesive , fibrin glue , chondrocyte , gelatin , cartilage , surgery , larynx , anatomy , dentistry , biomedical engineering , materials science , medicine , composite material , chemistry , biochemistry , layer (electronics)
Guinea pig laryngeal fractures were used as a model to compare the ease of application and effectiveness of the fibrinogen‐adhesive system with the case of application and effectiveness of cyanoacrylate glue and control fractures stinted with contralateral gelatin film. Seven fibrin adhesive‐treated and two cyanoacrylate glue‐treated guinea pigs were perfused after 60 and 35 days, respectively. The larynges were serial sectioned, and the wound sites were compared. The fibrinogen adhesive system was easier to dispense than cyanoacrylate glue, did not require a completely dry surface, and stabilized within 3 minutes. Cartilage segment alignment with focal, complete fracture healing and symmetrical chondrocyte proliferation were seen in fibrogen adhesive‐stinted larynges. In the cyanoacrylate glue‐treated larynges, there was no alignment and minimal, asymmetrical chondrocyte proliferation. Gelatin film‐stinted controls exhibited similar features. Thus, fibrogen adhesive was easier to apply and more effectively bound laryngeal fractures than cyanoacrylate glue or gelatin film.