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Chronic sinusitis and woodworking as risk factors for cancer of the maxillary sinus in Northeast Japan
Author(s) -
Shimizu Hiroyuki,
Hisamichi Shigeru,
Hozawa Jiro,
Saito Hisaki,
Murai Kazuo,
Hirata Hideto,
Takasaka Tomonori,
Togawa Kiyoshi,
Konno Akiyoshi,
Kimura Yo,
Kikuchi Akira,
Ohkouchi Yukio,
Ohtani Iwao
Publication year - 1989
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1288/00005537-198901000-00011
Subject(s) - medicine , dentistry , chronic sinusitis , sinusitis , maxillary sinus , basal cell , risk factor , cancer , relative risk , population , residence , environmental health , surgery , demography , confidence interval , sociology
In the period 1983 to 1985, 66 patients presented to six Japanese university hospitals with squamous cell carcinoma of the maxillary sinus. Using self‐administered questionnaires, a case‐control study was conducted to examine history of nasal diseases, occupational exposures, and other possible risk factors for this disease. For each patient, two controls were selected from the general population, matched to the patient by sex, age (± 5 years), and district of residence. A history of chronic sinusitis was associated with a 2.3‐fold increase in risk ( p = 0.05). A high relative risk was also observed in males with an occupational history of woodworking or joinery, particularly when these jobs involved sanding or lathing practices (RR = 7.5, p = 0.02). No association between cigarette smoking and maxillary sinus cancer was observed in this study and no evidence was found that indoor air pollution in the home is involved in cancer development.