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Minor salivary gland tumors of the lip and buccal mucosa
Author(s) -
Weber Randal S.,
Guillamondegui Oscar M.,
Byers Robert M.,
Palmer J. Mark,
ElNaggar Adel,
Mcneese Marsha D.
Publication year - 1989
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1288/00005537-198901000-00002
Subject(s) - adenoid cystic carcinoma , medicine , buccal mucosa , salivary gland , perineural invasion , radiation therapy , minor salivary glands , pathology , histology , carcinoma , buccal administration , cancer , oral mucosa , oral cavity , dentistry
Between 1944 and 1985, 50 patients with minor salivary gland tumors of the lip and buccal mucosa were treated at M. D. Anderson Cancer Center: 19 with lip and 31 with buccal mucosa tumors. The male‐to‐female ratios were 2.8:1 for lip and 1:2.9 for the buccal mucosa tumors. Patient age at presentation ranged from 18 to 98 years with a median of 55 years. Treatment consisted of surgery alone for 28 patients, radiotherapy in 9 patients, and combined therapy for 13. Adenoid cystic carcinoma was the predominant histologic type, accounting for 21 (42%) tumors. Risk for recurrence was influenced by histology, the presence of perineural invasion, and the location of the primary tumor. Six patients developed recurrent disease; all six had adenoid cystic carcinoma. The therapeutic approach and the rationale for combined treatment of these neoplasms are discussed.