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Role of aerobic and anaerobic microorganisms in chronic suppurative otitis media
Author(s) -
Papastavros Theodore,
Giamarellou Helen,
Varlejides Stratos
Publication year - 1986
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1288/00005537-198604000-00017
Subject(s) - gentamicin , anaerobic exercise , otitis , medicine , microbiology and biotechnology , chronic suppurative otitis media , intensive care medicine , biology , antibiotics , surgery , physiology
This study reports results of cultures of drainage from 119 cases with chronic otitis media. Mixed infections were found to occur 30 times more frequently among cholestcatomatous cases compared to noncholesteatomatous. A significant association was found between prior use of gentamicin ear drops and bacterial resistance to the drug. The role of aerobes and anaerobes in mixed infections of cholesteatomatous ears is discussed. The relevant literature is critically reviewed and the mechanisms of synergistic anaerobic infections of the ear are summarized. The need for animal studies of bacterial pathogenicity and parallel human studies of response to rational medicinal treatment is stressed.