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Autologous fibrin tissue adhesive
Author(s) -
Siedentop Karl H.,
Harris David M.,
Sanchez Ben
Publication year - 1985
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1288/00005537-198509000-00011
Subject(s) - adhesive , fibrin glue , fibrin , fibrin tissue adhesive , glue , ammonium sulfate , fibrinogen , bonding strength , biomedical engineering , autologous blood , materials science , surgery , chemistry , composite material , chromatography , medicine , layer (electronics) , immunology , biochemistry
Various methods of making fibrin tissue adhesive from a patient's own blood were evaluated. The method using ammonium sulfate for fibrinogen preparation produced the greatest bonding strength. The average bonding strength of the commercially manufactured adhesive and of the autologous fibrin tissue adhesive were compared at 10 minutes and 30 minutes after glucing together lxl cm samples of fresh human dura. Results indicate the commercial glue holding 57 gms/cm 2 at 10 minutes and 123 gms/cm 2 at 30 minutes, while autologous glue prepared with the “ammonium sulfate method” has a bonding strength of 41 gms/cm 2 at 10 minutes and 217 gms/cm 2 at 30 minutes.