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Adenoid cystic carcinoma of the nasopharynx after previous adenoid irradiation.
Author(s) -
Sofferman Robert A.,
Heisse John W.
Publication year - 1985
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1288/00005537-198504000-00016
Subject(s) - adenoid , adenoid cystic carcinoma , nasopharyngeal carcinoma , malignancy , medicine , incidence (geometry) , otorhinolaryngology , radiation therapy , radium , dermatology , carcinoma , oncology , pathology , surgery , physics , nuclear physics , optics
In 1978, Prntt challenged the otolaryngology community to identify an incidence of malignancy in individuals who have previously received radium therapy to the nasopharyngeal lymphoid tissues. This case report is a direct response to that quest and presents a well documented adenoid cystic carcinoma evolving 23 years after radium applicator treatment to the fossa of Rosenmuller. Although a cause‐and‐effect relationship cannot be scientifically proven, the case history raises several important questions concerning the stimulating effects of radiation on the later onset of frank malignancy.