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Histopathology of the temporal bone in osteogenesis imperfecta congenita: A report of 5 cases
Author(s) -
Berger Gilead,
Hawke Michael,
Johnson Alan,
Proops David
Publication year - 1985
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1288/00005537-198502000-00014
Subject(s) - otosclerosis , ossicles , stapes , osteogenesis imperfecta , temporal bone , ossification , medicine , anatomy , inner ear , histopathology , malleus , middle ear , vestibular system , stapedectomy , cochlea , pathology , audiology
The histopathologic findings in 8 temporal bones from 5 patients with osteogenesis imperfecta congenita are reported. The otic capsule, bony walls of middle ear, and ossicles showed evidence of both deficient and abnormal ossification. Microfractures were found in the otic capsule and in the anterior process and handle of the malleus, in addition to their common location at the crurn of the stapes. The cochlear and vestibular end‐organs appeared normal. Pathologic changes compatible with otosclerosis were not seen. The possible implication of these changes on hearing and balance is discussed.