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Sino‐Orbital aspergillosis associated with total ophthalmoplegia
Author(s) -
Yumoto Eiji,
Kitani Shinji,
Okamura Hlroshi,
Yanagihara Naoaki
Publication year - 1985
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1288/00005537-198502000-00013
Subject(s) - aspergillosis , medicine , orbit (dynamics) , paranasal sinuses , surgery , orbital diseases , computed tomography , engineering , immunology , computed tomographic , aerospace engineering
Invasive aspcrgillosis of the paranasal sinuses involving the orbit is termed sino‐orbital aspergillosis. Prognosis of sino‐orbital aspergillosis, complicated by impaired visual acuity and neurological signs, is disastrous and usually fatal. We herein report two patients with sino‐orbital aspergillosis associated with total ophthalmoplegia. One patient was successfully treated with surgical eradication including orbital exenteration. In contrast, the other died of cerebral infarction, probably due to fungal thrombosis of the middle cerebral artery, despite repeated local debridement followed by orbital exenteration and administration of antifungal agents. Experience with these cases strongly indicates the necessity of prompt surgical eradication, including orbital exenteration if necessary, in the treatment of sino‐orbital aspergillosis.