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Rhabdomyosarcoma of the head and neck
Author(s) -
Newman Anita N.,
Rice Dale H.
Publication year - 1984
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1288/00005537-198402000-00019
Subject(s) - medicine , rhabdomyosarcoma , head and neck , nodal , chemotherapy , surgery , biopsy , overall survival , radiation therapy , retrospective cohort study , radiology , sarcoma , pathology
Abstract A retrospective review of all cases of rhabdomyosarcoma seen at UCLA was done. Survival prior to the advent of cyclic multidrug chemotherapy was compared to survival with this therapy. In the latter group, unlike other published series, survival was 100% better with gross total removal of disease as compared to biopsy only. All received at least 5000 rods. Fifteen percent presented with regional nodal metastases. However 75% of these also had intracranial extension and all died. An additional 19% developed late regional nodal metastases; 80% of these also developed systemic metastases and all died. Survival in the absence of nodal disease was 41%.