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Control of malignant melanoma of the nasal mucous membrane
Author(s) -
Mcrae Robert G.,
Bellino Joseph P.,
Khasgiwala Chandra
Publication year - 1982
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1288/00005537-198211000-00004
Subject(s) - melanoma , otorhinolaryngology , medicine , mucous membrane , head and neck , head and neck surgery , mucosal melanoma , metastasis , malignant disease , dermatology , disease , surgery , nasal cavity , pathology , cancer , cancer research
Malignant melanoma of the nasal mucous membrane continues to be a rare disorder which is difficult to treat. Five year survival rate appears to be less than 30% and most patients who die of the disease have distant metastasis. At this time, the otolaryngologist and head and neck surgeon must strive to control local and regional disease with surgical means. Unfortunately, these means are usually inadequate because survival is critically dependent on the biology of the melanoma and its interaction with the patient's immune system.