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Ear disease in patients with wegener's granulomatosis
Author(s) -
Kornblut Alan D.,
Wolff Sheldon M.,
Fauci Anthony S.
Publication year - 1982
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1288/00005537-198207000-00001
Subject(s) - wegener granulomatosis , medicine , disease , granulomatosis with polyangiitis , dermatology , systemic disease , vasculitis , pathology
From a group of 60 patients with histologically‐proven Wegener's granulomatosis managed at the National Institute of Allergy and Infectious Disease, approximately 45% were found to have disease that involved the ears. The majority of these patients had either recurrent or persistent serous otitis, resulting from eustachian tube dysfunction as a consequence of nasopharyngeal inflammations. Other pathologies included suppurative otitis, cholesteatoma, facial nerve paralyses, temporal bone grnnulomata, and sensory hearing losses. The presentation and management of these changes and their relationships to underlying disease are described in selected case reports, and a general philosophy of patient management is presented.