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Lymphoepithelioma of the nasopharynx
Author(s) -
Applebaum Edward L.,
Mantravadi Prasad,
Haas Richard
Publication year - 1982
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1288/00005537-198205000-00009
Subject(s) - lymphoepithelioma , nasopharyngeal carcinoma , medicine , stage (stratigraphy) , basal cell , cervical lymph nodes , lymph node , lymphoepithelioma like carcinoma , carcinoma , oncology , pathology , radiation therapy , cancer , biology , epstein–barr virus , virus , immunology , metastasis , paleontology
There is uncertainty as to whether the clinical behavior of nasopharyngeal lymphoepithelioma differs from that of squamous cell carcinoma of the nasopharynx. To determine if significant differences existed, we have studied 39 patients with nasopharyngeal lymphoepithelioma and compared their data with 50 nasopharyngeal squamous cell carcinoma patients. In contrast to squamous cell carcinoma, lymphoepithelioma occurred at a younger age, presented as smaller primary tumors, and manifested more extensive cervical lymph node involvement. When analyzed by T stage, N stage, or overall stage groups, the 5‐year actuarial survivals were better in the lymphoepithelioma patients. Late tumor recurrences (beyond 4 years) were seen in the lymphoepithelioma patients, whereas all of the recurrences in the squamous cell carcinoma group occurred within 4 years. Tumor recurrences were more common in the cervical lymph nodes in the lymphoepithelioma group and in the primary site of the squamous cell carcinoma group.