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Clinical‐Pathological determinants in prognosis of fibrous histiocytomas of head and neck
Author(s) -
Blitzer Andrew,
Lawson William,
Zak Frederick G.,
Biller Hugh F.,
Som Max L.
Publication year - 1981
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1288/00005537-198112000-00008
Subject(s) - head and neck , pathological , medicine , pathology , giant cell , population , necrosis , surgery , environmental health
Review of the literature reveals 76 cases of fibrous histiocytoma of the deep structures of the head and neck. To this we have added 11 of our own cases, and analyzed the total group to determine clinical and histological features of a high risk population. Age, sex, presence of pain, location of tumor, size of tumor, and local invasion appear to be important clinical criteria. Bizarre giant cells, numerous and atypical mitoses, necrosis, and inflammation appear to be important histologic features. The treatment of choice is wide local excision. Chemotherapy appears to produce tumor regression.