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Malignant fibrous histiocytoma of the frontal sinus
Author(s) -
Schaefer Steven D.,
Denton Richard A.,
Blend Benjamin L.,
Carder Henry M.
Publication year - 1980
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1288/00005537-198012000-00013
Subject(s) - stroma , pathology , sinus (botany) , paranasal sinuses , mesenchymal stem cell , frontal sinus , medicine , ultrastructure , chemotherapy , radiation therapy , biology , radiology , immunohistochemistry , surgery , botany , genus
The first case of malignant fibrous histiocytoma of the frontal sinus is reported. The aggressive nature of the tumor despite its relatively benign histologic pattern and value of electron microscopy are emphasized. Ultrastructural examination reveals a progression of several principal cell types, lending support to the multi‐potent mesenchymal cell origin of these malignancies. These cells may have arisen from the supporting stroma of the ectodermally derived respiratory epithelium of the paranasal sinuses. Wide local excision is currently the primary mode of therapy. The value of radiation therapy or chemotherapy in this tumor is unproven.