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Effect of prophylactic antibiotics in radical head and neck surgery
Author(s) -
Goode Richard L.,
Abramson Norton,
Fee Willard E.,
Levine Paul
Publication year - 1979
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1288/00005537-197904000-00009
Subject(s) - antibiotics , cephalosporin , medicine , aminoglycoside , cephalosporin antibiotic , incidence (geometry) , head and neck surgery , head and neck , surgery , anesthesia , microbiology and biotechnology , otorhinolaryngology , biology , physics , optics
One hundred major head and neck operations performed on 77 patients were evaluated regarding the effectiveness of an aminoglycoside and cephalosporin antibiotic combination given prophylactically to prevent postoperative infection. The postoperative infection incidence was 6%, significantly lower than that reported in similar series where no antibiotics were used. The addition of the aminoglycoside did not appear to provide any additional protection compared with the use of cephalosporin alone.