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Laryngeal transplantation: Current status 1974
Author(s) -
Tucker Harvey M.
Publication year - 1975
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1288/00005537-197505000-00003
Subject(s) - transplantation , medicine , reinnervation , intensive care medicine , surgery , clinical practice , physical therapy
There are four major areas of concern that must be examined before human laryngeal transplantation can be considered feasible in clinical practice. These are: 1. surgical mechanics of revascularization; 2. reinnervation; 3. prevention of host rejection; and 4. justification. Of these criteria, the first two have been met successfully at present. Safe suppression of rejection without increased risk of cancer recurrence remains to be achieved. Until this third criterion is satisfied, one is probably not justified to make further attempts at laryngeal transplantation in humans.