Premium
Gallium‐67 scanning in patients with head and neck cancer
Author(s) -
Kashima Haskins K.,
Mckusick Kenneth A.,
Malmud Leon S.,
Wagner Henry N.
Publication year - 1974
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1288/00005537-197407000-00002
Subject(s) - gallium , head and neck cancer , head and neck , medicine , cancer , pathology , nuclear medicine , chemistry , surgery , organic chemistry
This study was undertaken to evaluate the use of Gallium‐67 scanning in the management of patients with malignancies in the head and neck region. The principal findings are: 1. Gallium‐67 accumulates preferentially in the lacrimal and salivary glands in a high proportion of cases and, almost invariably, in the mid‐facial zone; 2. the uptake by the lacrimal and salivary glands is permanently enhanced by prior radiation therapy; 3. tumor identification is reliable, providing that the tumor focus measures at least 2 centimeters in diameter; 4. non‐specific inflammation also accumulates this isotope; and 5. tissue analysis reveals consistently elevated Gallium‐67 concentration in tumor. These characteristics of Gallium‐67 may lead to its eventual useful role in the evaluation of patients with head and neck cancers.