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Suppression of rabbit ear skin homograft rejections with sheep anti‐thymus globulins. A preliminary report
Author(s) -
David Lyle A.,
Davidenas Joseph A.,
Ogura Joseph H.
Publication year - 1973
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1288/00005537-197303000-00005
Subject(s) - globulin , rabbit (cipher) , antibody , gamma globulin , biology , immunology , statistics , mathematics
Two electrophorectically distinct “7s” γ 1 , and γ 2 globulins were isolated from sheep anti‐rabbit thymus serum. The γ 1 fraction was effective in prolonging skin homograft retention in rabbits but did not suppress humoral antibody formation. The γ 2 fraction appears to contain other antibodies which react with rabbit tissue to cause anaphylactic‐like reactions.