Open AccessEffects of multicomponent interventions on biochemical markers in obese youth: a systematic review protocol
Author(s) -
Letícia Borfe,
Paulo Henrique Guerra,
Cézane Priscila Reuter,
Caroline Brand,
José Francisco López Gil,
Javier Brazo-Sayavera,
Anelise Reis Gaya
Publication year - 2021
Publication title -
revista brasileira de atividade física e saúde
Language(s) - English
Resource type - Journals
eISSN - 2317-1634
pISSN - 1413-3482
DOI - 10.12820/rbafs.26e0220
Subject(s) - psychological intervention , scopus , medicine , protocol (science) , meta analysis , obesity , medline , randomized controlled trial , leptin , web of science , clinical psychology , physical therapy , psychology , gerontology , alternative medicine , pathology , psychiatry , biology , biochemistry
Physical exercise is effective in modulating circulating inflammatory markers of obesity. However, little is known about the effects of interventions with physical exercise programs accompanied by nutritional and/or psychological guidance, configuring themselves as multicomponent programs. Thus, the aim of this review is to systematically evaluate the evidence related to the effects of multicomponent weight-loss interventions in modulating circulating inflammatory markers in children and adolescents. Therefore, the following databases will be searched to identify all relevant articles: PubMed, SciELO, Lilacs, Web of Science, EMBASE, Scopus, SPORT Discus. Randomized controlled trials and quasi-experimental studies of children and adolescents (6 to 18 years old) will be included. Eligible interventions will target weight-related behaviors (including diet, physical activity, behavior modification and/or combinations thereof). Two independent reviewers will select studies using Rayyan QCRI software and extract the data to a standard form. The main outcomes of the review will be the circulating values of leptin, interleukin 6 (IL-6) and tumor necrosis factor-alpha (TNF- α) in a quantitative way. To assess the methodological quality (or risk of bias) of individual studies, Effective Public Health Practice Project assessment tool will be used. The meta-analysis will be performed using the Review Manager software.