Open AccessIs NPH associated with fewer adverse events than analog basal insulin for adults with T2D?
Author(s) -
Corey Lyon,
Swetha Iruku,
Molly Hoss,
Kristen DeSanto,
Richard Guthmann
Publication year - 2021
Publication title -
the journal of family practice
Language(s) - English
Resource type - Journals
eISSN - 1533-7294
DOI - 10.12788/jfp.0191
Subject(s) - medicine , hypoglycemia , insulin glargine , observational study , randomized controlled trial , emergency department , adverse effect , nph insulin , insulin , basal insulin , pediatrics , basal (medicine) , intensive care medicine , emergency medicine , type 2 diabetes , diabetes mellitus , endocrinology , psychiatry
NO. Insulin glargine may lead to less patient-reported, symptomatic, and nocturnal hypoglycemia, although overall, there may not be a difference in the risk for severe hypoglycemia orhypoglycemiarelated emergency department (ED) visits and hospitalizations (strength of recommendation [SOR]: B, systematic review of randomized controlled trials [RCTs], individual RCTs, and observational study).