Open AccessCutaneous Manifestations of COVID-19: Characteristics, Pathogenesis, and the Role of Dermatology in the Pandemic
Author(s) -
Mariam Alam,
William D. Lewis,
Joanna Harp,
Katherine T. Steele,
Misha Rosenbach,
Robert G. Micheletti
Publication year - 2021
Publication title -
cutis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.289
H-Index - 53
eISSN - 2326-6929
pISSN - 0011-4162
DOI - 10.12788/cutis.0230
Subject(s) - medicine , covid-19 , kawasaki disease , purpura (gastropod) , disease , dermatology , pandemic , pathogenesis , pathophysiology , immunology , pathology , infectious disease (medical specialty) , outbreak , ecology , surgery , artery , biology
Cutaneous manifestations of COVID-19-SARS-CoV-2-are common and varied. Morbilliform, vesicular, and urticarial eruptions may be nonspecific initial features of the disease. Chilblainlike lesions on the fingers or toes typically occur as part of a resolution phase, signifying a milder course, whereas livedoid lesions and retiform purpura are associated with coaguloapthy and more severe disease. Additionally, a severe Kawasaki-like multisystem inflammatory syndrome rarely is seen in children. This diverse range of cutaneous manifestations in COVID-19 reflects a spectrum of host immunologic responses to SARS-CoV-2 and may inform disease pathophysiology.