Open AccessWild transthyretin amyloid cardiomyopathy recognition with noninvasive strategies: a case report and diagnostic approach for transthyretin-related cardiomyopathy
Author(s) -
Gaspar Del RioPertuz,
Leigh Ann Jenkins,
Pooja Sethi,
Erwin Argueta-Sosa
Publication year - 2022
Publication title -
the southwest respiratory and critical care chronicles
Language(s) - English
Resource type - Journals
ISSN - 2325-9205
DOI - 10.12746/swrccc.v10i42.999
Subject(s) - transthyretin , cardiomyopathy , medicine , amyloid (mycology) , cardiology , restrictive cardiomyopathy , biopsy , heart failure , pathology
Recent studies suggest that the prevalence of wild type transthyretin cardiomyopathy (wATTR-CM) is substantially higher than previously appreciated in older adults with heart failure. Advances in nuclear imaging using bone avid radiotracers permit diagnosis of transthyretin-related cardiomyopathy (ATTR-CM) without a tissue biopsy. We describe two wATTR-CM cases that were diagnosed using noninvasive methods and demonstrate this diagnostic approach for transthyretin-related cardiomyopathy.
Key words: amyloid, cardiomyopathy