Open AccessMORPHOMETRIC FEATURES OF TERMINAL VILLI IN PRETERM PLACENTA
Author(s) -
О. В. Островская,
О. V. Ostrovskaya,
О. В. Кожарская,
Ol'ga Kozharskaya,
С. В. Супрун,
Stefaniya Suprun,
Денис Мусатов,
Денис Мусатов,
Виктория Обухова,
Viktoriya Obuhova,
Н. М. Ивахнишина,
Natalya Ivakhnishina,
Е Б Наговицына,
Е Б Наговицына,
М. А. Власова,
М. А. Власова,
О. А. Лебедько,
О. А. Лебедько
Publication year - 2018
Publication title -
bûlletenʹ fiziologii i patologii dyhaniâ
Language(s) - English
Resource type - Journals
ISSN - 1998-5029
DOI - 10.12737/article_5c1269c4350159.55377375
Subject(s) - syncytiotrophoblast , placenta , pregnancy , hypoxia (environmental) , andrology , chorionic villi , obstetrics , full term , biology , fetus , medicine , chemistry , genetics , organic chemistry , oxygen
In this study, morphometric features of terminal villi in term and preterm placentas were compared. Placentas of 13 patients whose pregnancy ended in premature birth and placentas of 35 women with physiological pregnancy and delivery at term were studied. Morphometric assessment was made with Carl Zeiss Axio Imager microscope using an image analysis software package. The number of capillaries in terminal villi of preterm placentas was found to be decreased, while the vessels-to-syncytiotrophoblast distance was found to be increased. These result in a decreased gas exchange between maternal blood and placental tissue, hypoxia and can cause early termination of pregnancy. Mean values of cross-sectional area, vertical dimension and perimeter of terminal villi in preterm placentas are found to be greater than those in term placentas, which contributed to an increase in gas exchange area and can be regarded as a compensatory reaction at a tissue level.