Open AccessCARDIAC LESION IN CHURG – STRAUSS SYNDROME
Author(s) -
Каня,
O. V. Kanya,
Гуртовая,
Galina Gurtovaya,
Енисеева,
Е. С. Енисеева,
Стефаненкова,
А. А. Стефаненкова
Publication year - 2016
Publication title -
bûlletenʹ vostočno-sibirskogo naučnogo centra
Language(s) - English
Resource type - Journals
ISSN - 1811-0649
DOI - 10.12737/23843
Subject(s) - medicine , eosinophilia , granulomatosis with polyangiitis , eosinophilic , vasculitis , myocardial infarction , pathology , eosinophil , necrotizing vasculitis , cardiology , hypereosinophilia , endocardium , pericardium , asthma , disease
Cardiac involvement is the most important prognostic factor in eosinophilic granulomatosis with polyangiitis (Churg–Strauss syndrome). We report a case of Churg–Strauss syndrome in 65-year-old women masquerading as a non-ST elevation myocardial infarction. She had chest discomfort, dyspnea and ST depression, high troponin level and so myocardial infarction was diagnosed. She had had asthma for 4 years but had no eosinophilia in peripheral blood and lesions in the lungs at the time of the first hospitalization. Her skin was clean without rashes. 3 months later she was hospitalized again having pulmonary infiltrates. Laboratory tests revealed that eosinophil was significantly increased. Cardiac involvement in a pathological process led to death. Histological examination of heart and lungs showed necrotic coronary vasculitis, granulomas and perivascular eosinophilic infiltrates in myocardium, endocardium, pericardium and pulmonary eosinophilic infiltrates.