Open Access
ABNORMALITY OF LIPID METABOLISM IN PATIENTS WITH DIABETES MELLITUS TYPE 1 AND POOR GLYCEMIC CONTROL WITH AND WITHOUT DIABETIC MICROANGIOPATHIES
Author(s) -
Владимир Сергеевич Съемщиков,
Л. Ю. Хамнуева,
Elena Chugunova
Publication year - 2016
Publication title -
bûlletenʹ vostočno-sibirskogo naučnogo centra
Language(s) - English
Resource type - Journals
ISSN - 1811-0649
DOI - 10.12737/23790
Subject(s) - dyslipidemia , medicine , glycemic , diabetes mellitus , lipid metabolism , endocrinology , glycated hemoglobin , type 1 diabetes , lipid profile , metabolic control analysis , type 2 diabetes mellitus , triglyceride , gastroenterology , cholesterol , type 2 diabetes
Hyperglycemia and dyslipidemia are common metabolic abnormalities in adults with type 1 diabetes mellitus (T1DM) and both increase cardiovascular disease risk. Normalization of lipid metabolism is a mandatory element in preven-tion of diabetic micro- and macroangiopathies in patients with T1DM and it is directly related to improvement of health outcome. We aimed to investigate serum lipid profiles in patients with T1DM and poor glycemic control. Among observed patients with T1DM, 76% were classified as having dyslipidemia, dyslipidemia rate was higher in patients with diabetic microangiopathies. Patients with T1DM and microvascular complications, arterial hypertension (AH) and the level of glycated hemoglobin (HbA1c) >8% had significantly higher levels of total cholesterol (TC), very low density lipoproteins (VLDL), triglycerides (TG) and non-high density lipoproteins (non-HDL). Therefore, management of patients with T1DM at the outpatient stage requires a strict control of lipid metabolism.