Open AccessProliferative activity of salivary tumor cells
Author(s) -
Немчинова,
Svetlaemchinova,
Раевская,
Lidiya Raevskaya,
Казимирский,
Viktor Kazimirskiy,
Кислицина,
Lada Kislitsina,
Алёшкин,
Igor Aleshkin,
Батороев,
Yuriy Batoroev,
Бычков,
Д. А. Бычков,
Фильченкова,
Elena Filchenkova
Publication year - 2016
Publication title -
bûlletenʹ vostočno-sibirskogo naučnogo centra
Language(s) - English
Resource type - Journals
ISSN - 1811-0649
DOI - 10.12737/23393
Subject(s) - pathology , fine needle aspiration , medicine , head and neck , salivary gland , cytology , tumor cells , differential diagnosis , cancer research , biopsy , surgery
Salivary carcinomas comprise 2–3 % of malignant tumors of the head and neck. The basic method of morphological study in early diagnostics is aspiration puncture with a fine needle (FNAB). Complex histologic structure and great diversity of morphological items complicate cytologic diagnostics of salivary tumors considerably. Immunocytochemical examination must be used to reduce the errors, it enables to reveal neoplastic cells at early stages of malignization. High proliferative activity of tumor cells is one of their biological peculiarities. Accuracy in differential diagnostics between benign and malignant tumors is improved through determination of mitotic index combined with a fine needle aspiration puncture.