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Proliferative activity of salivary tumor cells
Author(s) -
Немчинова,
Svetlaemchinova,
Раевская,
Lidiya Raevskaya,
Казимирский,
Viktor Kazimirskiy,
Кислицина,
Lada Kislitsina,
Алёшкин,
Igor Aleshkin,
Батороев,
Yuriy Batoroev,
Бычков,
D. A. Bychkov,
Фильченкова,
Elena Filchenkova
Publication year - 2016
Publication title -
бюллетень восточно-сибирского научного центра сибирского отделения российской академии медицинских наук
Language(s) - English
Resource type - Journals
ISSN - 1811-0649
DOI - 10.12737/23393
Subject(s) - pathology , fine needle aspiration , medicine , salivary gland , head and neck , tumor cells , cytology , differential diagnosis , cancer research , biopsy , surgery
Salivary carcinomas comprise 2–3 % of malignant tumors of the head and neck. The basic method of morphological study in early diagnostics is aspiration puncture with a fine needle (FNAB). Complex histologic structure and great diversity of morphological items complicate cytologic diagnostics of salivary tumors considerably. Immunocytochemical examination must be used to reduce the errors, it enables to reveal neoplastic cells at early stages of malignization. High proliferative activity of tumor cells is one of their biological peculiarities. Accuracy in differential diagnostics between benign and malignant tumors is improved through determination of mitotic index combined with a fine needle aspiration puncture.

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