Open Accesscharacteristics of liver enzyme in various pathologies of the pancreas
Author(s) -
Дьякович,
O. A. Dyakovich,
; Кузнецова,
Yulia Kuznetsova
Publication year - 2016
Publication title -
bûlletenʹ vostočno-sibirskogo naučnogo centra
Language(s) - English
Resource type - Journals
ISSN - 1811-0649
DOI - 10.12737/23343
Subject(s) - endocrine system , medicine , pancreatitis , fatty liver , pancreas , liver function , gastroenterology , exacerbation , liver function tests , liver disease , endocrinology , enzyme , disease , biology , hormone , biochemistry
Diseases caused by disturbance of endogenous and exogenous pancreatic functions (endocrine function – diabetes mel-litus (DM) and exocrine function – chronic pancreatitis (CP)), are widely distributed in the world due to alcohol abuse, unhealthy lifestyle and negative influence of the environment. These pathologies often associate with abnormal liver functions. The goal of the study was to explore the features of the liver enzymes in 47 patients with a diagnosis of DM and CP. We revealed increase in the content of liver enzymes (aspartate aminotransferase, alanine aminotransferase, gamma-glutamyl transferase) in disturbance of pancreatic endocrine function. This dysfunction may be caused by hepatitis B and C, and fatty liver disease. Concentration of liver enzymes in the blood of individuals with hepatitis B and C was also increased. Levels of liver enzymes in patients with exocrine pathology ranged in the reference values. The reason could be the remission of CP in the examined patients. These studies require involvement of larger number of patients with the remission of the disease, and a new group of patients with CP exacerbation stage. Also additional functional and biochemical studies are necessary to identify the diagnosis of fatty liver.